| 09.30 |
REGISTRATION & REFRESHMENTS |
| 10.00 |
Introduction to Nutrition Day
Prof Martin Wickham, Head of Nutrition, Leatherhead |
| 10.10 |
Welcome to Leatherhead
Dr Paul Berryman, Chief Executive, Leatherhead |
| 10.25 |
Health Claim Substantiation: An Industry Perspective
Dr Julian Stowell, Vice President, Scientific Affairs, Health & Nutrition, Danisco (UK) Ltd |
| 10.55 |
Designing Trials for Health Claim Substantiation
Dr Roberta Re, Nutrition Research Manager, Leatherhead
Many health claims submitted to EFSA have been rejected due to insufficient data or because no cause and effect can be determined. This is proving a bigger challenge than predicted for the food industry. A strong scientific body of evidence, including at least one human intervention study, is required and careful consideration must be given when designing clinical trials for a health claim. Selection of the population, choosing appropriate controls, study power, selection of relevant endpoints and accepted biomarkers as well as mode of use are key components of this process. This presentation will describe these key components and identify the main challenges associated with designing trials for health claim substantiation. |
| 11.25 |
REFRESHMENTS & NETWORKING |
| 11.50 |
Introduction to Forum Research & 2012 Forum Projects
Sarah Hull, Forum Liaison Officer, Nutrition Research, Leatherhead
Sarah will give an overview of the Forum Research programme, explain the voting system and demonstrate how Leatherhead members can guide the Forum Research. This presentation will also describe several ongoing projects being carried out by the Nutrition & Health Forum for 2012: "Macronutrient absorption from food: the measured energy (metabolisable energy) value of foods in the human diet" and "Designing food structure for satiety - food to make you full!", a joint project between the Ingredients and Nutrition & Health Forums. |
| 12.05 |
Forum Research: The influence of Cereal Fibre on Vascular Function
Sarah Kuczora, Nutritionist, Nutrition Research, Leatherhead
Sarah will give an overview of the 2009-2011 forum project “Cereal fibre consumption and vascular function in overweight individuals”. The literature review conducted in year one demonstrated that in epidemiological studies wholegrain cereal products, as opposed to the combination of both refined and wholegrain cereals, provide the greatest protection against cardiovascular disease. The protective effects of wholegrains likely originate from the synergistic action of compounds contained within wholegrain cereals, including fibre, but also a number of other bioactive components. The human intervention study in year two aimed to investigate the effect of integrating the diet with 3 servings (48g) of wholegrain per day on flow mediated dilation (FMD) over a 12 week period. The secondary objective was to assess the correlation between FMD measurements and other markers of cardiovascular function. |
| 12.25 |
Forum research: Validation of sample collection methodology for insulin analysis
Sonia Pombo, Senior Nutritionist, Nutrition Research, Leatherhead
Sustained energy release and glycaemic response to food have become a focus of attention for the food industry. A universal protocol for measuring glucose has been established, with capillary blood samples being the most reliable source. When looking at insulin response however, there is no literature to suggest a preferred method of sample collection. This forum project looks at the differences in insulin response using samples taken from capillary and venous blood. |
| 12.45 |
Forum research: Enhancing the bioaccessibility of functional nutrients
Dr Martin Wickham, Head of Nutrition, Leatherhead
The primary aim of this research project is to understand how fundamental food structure/matrix influences the bioaccessibility of model nutrients. The secondary aim is to try and correlate in vitro bioaccessibility as a predictive model of in vivo bioavailability. Using components found in prickly pear pulp as model compounds, four food matrices containing a mixture of the phytochemicals betanin and indicaxanthin will be investigated to determine the effect of food matrix on bioaccessibility in vitro. The outcome of this research will be used to design an in vivo bioavailability study. This presentation will describe the progress to date and ongoing research. |
| 13.05 |
LUNCH and Tours of the Nutrition Unit |
| 14.00 |
Health Claims: A Commission Perspective
Speaker to be confirmed |
| 14.30 |
Experiences from the NDA Panel
Professor Ambroise Martin, Claude Bernard University – Lyon
The great number of opinions on generic or specific claims published by EFSA raises the possibility of a better understanding of the rationale behind claim substantiation. From these opinions, the presentation will discuss the three very important and interrelated issues that should be carefully addressed in the submitted dossiers. The characterization of the food (in relation to the claimed effect and taking into account confounding components for which similar claims have already been accepted), and the characterization of the beneficial effect form the basis for the selection of appropriate published studies or the design of high quality proprietary studies for the substantiation of the claim, which, however, are always assessed in the light of the totality of the available scientific evidence. |
| 15.00 |
Panel Discussion & Debate on Health Claims |
| 15.30 |
CLOSE |
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